BDBM50156074 1,2-bis(3-fluorobenzylidene)hydrazine::CHEMBL371811::N,N''-Bis-[1-(3-fluoro-phenyl)-meth-(E)-ylidene]-hydrazine
SMILES Fc1cccc(\C=N\N=C\c2cccc(F)c2)c1
InChI Key InChIKey=YYMCVDNIIFNDJK-BEQMOXJMSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50156074
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataEC50: 2.60E+3nMAssay Description:Positive allosteric modulator activity at human muscarinic acetylcholine receptor M5 expressed in CHO cells by fluorometric imaging plate readerMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 2.36nMAssay Description:Effective concentration against metabotropic glutamate receptor 5 of human transfected into CHO cellsMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataEC50: 2.60E+3nMAssay Description:Positive allosteric modulation of mGluR5 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.36E+5nMAssay Description:Positive allosteric modulation at mGluR5 in mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 1 hr prior to LPS chall...More data for this Ligand-Target Pair
Affinity DataIC50: 1.36E+5nMAssay Description:Positive allosteric modulator activity at mGluR5 in mouse BV2 cells assessed as inhibition of nitric oxide production pre-treated 1 hr before lipopol...More data for this Ligand-Target Pair