BDBM50156212 2-(3,4-Dimethoxy-phenyl)-2-isopropyl-5-[1-(2-phenoxy-ethyl)-piperidin-4-ylamino]-pentanenitrile; hydrochloride::CHEMBL536956

SMILES COc1ccc(cc1OC)C(CCCNC1CCN(CCOc2ccccc2)CC1)(C#N)C(C)C

InChI Key InChIKey=BSKYKYIKSBDIDH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50156212   

TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50156212(2-(3,4-Dimethoxy-phenyl)-2-isopropyl-5-[1-(2-pheno...)
Affinity DataIC50:  3.10E+3nMAssay Description:In vitro antagonism of N-type calcium channels expressed in PC12 cells was determined as the increase in intracellular calcium influx in the presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50156212(2-(3,4-Dimethoxy-phenyl)-2-isopropyl-5-[1-(2-pheno...)
Affinity DataIC50:  3.80E+3nMAssay Description:In vitro antagonism of N-type calcium channels expressed in PC12 cells was determined as the increase in intracellular calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed