BDBM50157371 CHEMBL180486::N-((R)-1-{4-[4-(2,3-Dihydro-benzo[1,4]dioxin-6-ylsulfanyl)-3-trifluoromethyl-phenyl]-pyridin-2-yl}-pyrrolidin-3-yl)-N-methyl-acetamide

SMILES CN([C@@H]1CCN(C1)c1cc(ccn1)-c1ccc(Sc2ccc3OCCOc3c2)c(c1)C(F)(F)F)C(C)=O

InChI Key InChIKey=VWDMVVKQHNPLEH-HXUWFJFHSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50157371   

TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50157371(CHEMBL180486 | N-((R)-1-{4-[4-(2,3-Dihydro-benzo[1...)
Affinity DataIC50:  168nMAssay Description:Inhibitory concentration against integrin LFA-1/ICAM-1 binding complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed