BDBM50157419 (R)-1-{6-[4-(2-Isopropyl-phenylsulfanyl)-3-trifluoromethyl-phenyl]-pyrimidin-4-yl}-pyrrolidin-3-ol::CHEMBL368031

SMILES CC(C)c1ccccc1Sc1ccc(cc1C(F)(F)F)-c1cc(ncn1)N1CC[C@@H](O)C1

InChI Key InChIKey=VJRMETDTVGHPMG-QGZVFWFLSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50157419   

TargetIntegrin alpha-L/Intercellular adhesion molecule 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50157419((R)-1-{6-[4-(2-Isopropyl-phenylsulfanyl)-3-trifluo...)
Affinity DataIC50:  158nMAssay Description:Inhibitory concentration against integrin LFA-1/ICAM-1 binding complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed