BDBM50157707 CHEMBL3787359

SMILES C\C(=C/c1nc(Cn2cnc3ncccc3c2=O)no1)c1ccc(Cl)cc1

InChI Key InChIKey=IWTIXSBYEURJEK-FMIVXFBMSA-N

Data  4 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50157707   

LigandPNGBDBM50157707(CHEMBL3787359)
Affinity DataIC50:  116nMAssay Description:Antagonist activity at human TRPA1 expressed in tetracycline-inducible T-REx expression system transfected CHO cells assessed as inhibition of AITC-i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50157707(CHEMBL3787359)
Affinity DataIC50:  105nMAssay Description:Antagonist activity at rat TRPA1 expressed in tetracycline-inducible T-REx expression system transfected CHO cells assessed as inhibition of AITC-ind...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50157707(CHEMBL3787359)
Affinity DataEC50: >4.00E+4nMAssay Description:Agonist activity at human TRPA1 expressed in tetracycline-inducible T-REx expression system transfected CHO cells by 45Ca2+ uptake assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50157707(CHEMBL3787359)
Affinity DataIC50:  85nMAssay Description:Antagonist activity at human TRPA1 expressed in tetracycline-inducible T-REx expression system transfected CHO cells assessed as inhibition of AITC-i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50157707(CHEMBL3787359)
Affinity DataEC50: >4.00E+4nMAssay Description:Agonist activity at rat TRPA1 expressed in tetracycline-inducible T-REx expression system transfected CHO cells by 45Ca2+ uptake assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50157707(CHEMBL3787359)
Affinity DataIC50:  53nMAssay Description:Antagonist activity at rat TRPA1 expressed in tetracycline-inducible T-REx expression system transfected CHO cells assessed as inhibition of AITC-ind...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed