BDBM50157850 3-Hydroxy-1-phenyl-1H-thieno[2,3-d]pyrimidine-2,4-dione::CHEMBL182974

SMILES On1c(=O)n(Cc2ccccc2)c2sccc2c1=O

InChI Key InChIKey=YGSHEPGNPDRIPY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50157850   

TargetDNA excision repair protein ERCC-5(Homo sapiens (Human))
Athersys

Curated by ChEMBL
LigandPNGBDBM50157850(3-Hydroxy-1-phenyl-1H-thieno[2,3-d]pyrimidine-2,4-...)
Affinity DataIC50:  2nMAssay Description:Inhibitory concentration against the xeroderma pigmentosum GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyribonuclease-1(Homo sapiens (Human))
Mrc Technology

Curated by ChEMBL
LigandPNGBDBM50157850(3-Hydroxy-1-phenyl-1H-thieno[2,3-d]pyrimidine-2,4-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of DNAse1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFlap endonuclease 1(Homo sapiens (Human))
Mrc Technology

Curated by ChEMBL
LigandPNGBDBM50157850(3-Hydroxy-1-phenyl-1H-thieno[2,3-d]pyrimidine-2,4-...)
Affinity DataIC50:  680nMAssay Description:Inhibition of FEN1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFlap endonuclease 1(Homo sapiens (Human))
Mrc Technology

Curated by ChEMBL
LigandPNGBDBM50157850(3-Hydroxy-1-phenyl-1H-thieno[2,3-d]pyrimidine-2,4-...)
Affinity DataIC50:  0.230nMAssay Description:Inhibitory concentration against the Flap endonuclease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed