BDBM50157856 CHEMBL182332::[3-(5-Amino-pentyl)-2-(biphenyl-4-ylamino)-3,4-dihydro-quinazolin-4-yl]-acetic acid methyl ester::methyl 2-(3-(5-aminopentyl)-2-(biphenyl-4-ylamino)-3,4-dihydroquinazolin-4-yl)acetate

SMILES COC(=O)CC1N(CCCCCN)C(Nc2ccc(cc2)-c2ccccc2)=Nc2ccccc12

InChI Key InChIKey=BZIVJYCHNPZJHO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50157856   

TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50157856(CHEMBL182332 | [3-(5-Amino-pentyl)-2-(biphenyl-4-y...)
Affinity DataIC50:  300nMAssay Description:Inhibition of human T-type calcium channel alpha1G in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50157856(CHEMBL182332 | [3-(5-Amino-pentyl)-2-(biphenyl-4-y...)
Affinity DataIC50:  300nMAssay Description:Inhibition of T-type [Ca2+] channel (alpha1G) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50157856(CHEMBL182332 | [3-(5-Amino-pentyl)-2-(biphenyl-4-y...)
Affinity DataIC50:  300nMAssay Description:Inhibition of T-type calcium channel Cav3.1 alpha1G expressed in HEK293 cells by whole cell patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed