BDBM50157857 2-(2-(5-aminopentylamino)-3-(biphenyl-4-yl)-3,4-dihydroquinazolin-4-yl)-N-benzylacetamide::2-[2-(5-Amino-pentylamino)-3-biphenyl-4-yl-3,4-dihydro-quinazolin-4-yl]-N-benzyl-acetamide::CHEMBL425534::KYS-05050

SMILES NCCCCCNC1=Nc2ccccc2C(CC(=O)NCc2ccccc2)N1c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=PHOBNPDRNIKURV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50157857   

TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50157857(2-(2-(5-aminopentylamino)-3-(biphenyl-4-yl)-3,4-di...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human T-type calcium channel alpha1G in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50157857(2-(2-(5-aminopentylamino)-3-(biphenyl-4-yl)-3,4-di...)
Affinity DataIC50:  130nMAssay Description:Inhibition of T-type [Ca2+] channel (alpha1G) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50157857(2-(2-(5-aminopentylamino)-3-(biphenyl-4-yl)-3,4-di...)
Affinity DataIC50:  130nMAssay Description:Inhibition of T-type calcium channel Cav3.1 expressed in HEK293 cells coexpressing alpha1G subunit by whole-cell patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed