BDBM50157864 CHEMBL51435::tert-butyl 5-(4-(2-(benzylamino)-2-oxoethyl)-3-(biphenyl-4-yl)-3,4-dihydroquinazolin-2-ylamino)pentylcarbamate::{5-[4-(Benzylcarbamoyl-methyl)-3-biphenyl-4-yl-3,4-dihydro-quinazolin-2-ylamino]-pentyl}-carbamic acid tert-butyl ester

SMILES CC(C)(C)OC(=O)NCCCCCNC1=Nc2ccccc2C(CC(=O)NCc2ccccc2)N1c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=BMCLTRZPRHKBKB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50157864   

TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50157864(CHEMBL51435 | tert-butyl 5-(4-(2-(benzylamino)-2-o...)
Affinity DataIC50:  160nMAssay Description:Inhibition of human T-type calcium channel alpha1G in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50157864(CHEMBL51435 | tert-butyl 5-(4-(2-(benzylamino)-2-o...)
Affinity DataIC50:  160nMAssay Description:Inhibition of T-type [Ca2+] channel (alpha1G) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50157864(CHEMBL51435 | tert-butyl 5-(4-(2-(benzylamino)-2-o...)
Affinity DataIC50:  160nMAssay Description:Inhibition of T-type calcium channel Cav3.1 alpha1G expressed in HEK293 cells by whole cell patch-clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed