BDBM50159145 CHEMBL3786685

SMILES CC1(O)CCN(Cc2ccc(OC3CN(C3)C(=O)c3nnc(o3)-c3ccccc3)cc2)C1

InChI Key InChIKey=ZJUPVLQHLOIMEV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50159145   

TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50159145(CHEMBL3786685)
Affinity DataIC50:  22nMAssay Description:Antagonist activity at human MCHR1 expressed in CHO cell membranes preincubated for 5 mins followed by addition of MCH peptide measured after 45 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Mus musculus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50159145(CHEMBL3786685)
Affinity DataIC50:  6nMAssay Description:Displacement of [125I]Tyr13-MCH from mouse MCHR1 after 60 mins by microbeta scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50159145(CHEMBL3786685)
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibition of human ERG by IonWork assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed