BDBM50160351 2-(3,4-Dichloro-benzylamino)-7-(4-hydroxy-butyl)-1,7-dihydro-purin-6-one::CHEMBL182401

SMILES OCCCCn1cnc2nc(NCc3ccc(Cl)c(Cl)c3)[nH]c(=O)c12

InChI Key InChIKey=SIJYBMLNZYHCPV-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50160351   

TargetDNA polymerase III subunit alpha(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50160351(2-(3,4-Dichloro-benzylamino)-7-(4-hydroxy-butyl)-1...)
Affinity DataKi:  63nMAssay Description:Inhibitory constant against DNA polymerases IIIE from Bacillus subtilis; (a)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III PolC-type(Bacillus subtilis)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50160351(2-(3,4-Dichloro-benzylamino)-7-(4-hydroxy-butyl)-1...)
Affinity DataKi:  190nMAssay Description:Inhibitory constant against DNA polymerases IIIC produced by Bacillus subtilis; (a)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase III subunit alpha(Escherichia coli)
Glsynthesis

Curated by ChEMBL
LigandPNGBDBM50160351(2-(3,4-Dichloro-benzylamino)-7-(4-hydroxy-butyl)-1...)
Affinity DataKi:  8.60E+4nMAssay Description:Inhibitory constant against DNA polymerases IIIE from Escherichia coli; (a)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed