BDBM50160532 CHEMBL3785862

SMILES [H][C@@]12CC[C@](C)([C@H](C1)Nc1ncnc3c1nn1ccccc31)C2(C)C

InChI Key InChIKey=GDUXPMQWYZXXTB-SPKLELGKSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50160532   

TargetMetabotropic glutamate receptor 1(RAT)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50160532(CHEMBL3785862)
Affinity DataIC50:  1.61E+3nMAssay Description:Negative allosteric modulation of rat mGluR1 expressed in HEK293 cells assessed as inhibition of glutamate induced calcium mobilization by calcium mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50160532(CHEMBL3785862)
Affinity DataIC50: <3.16E+4nMAssay Description:Negative allosteric modulation of rat mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate induced calcium mobilization by calcium mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50160532(CHEMBL3785862)
Affinity DataIC50:  1.62E+3nMAssay Description:Negative allosteric modulation of rat mGluR1 expressed in HEK293 cells assessed as inhibition of glutamate induced calcium mobilization by calcium mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50160532(CHEMBL3785862)
Affinity DataIC50: >3.00E+4nMAssay Description:Negative allosteric modulation of rat mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate induced calcium mobilization by calcium mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed