BDBM50161781 3-{6-[2-(6-Methylamino-pyridin-2-yl)-ethoxy]-benzo[b]thiophen-3-yl}-propionic acid::CHEMBL178720

SMILES CNc1cccc(CCOc2ccc3c(CCC(O)=O)csc3c2)n1

InChI Key InChIKey=YJJAVNJAKKVPJI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50161781   

TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50161781(3-{6-[2-(6-Methylamino-pyridin-2-yl)-ethoxy]-benzo...)
Affinity DataIC50: >2.00E+4nMAssay Description:In vitro inhibition of human alphaIIb betaIIIa integrin binding in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50161781(3-{6-[2-(6-Methylamino-pyridin-2-yl)-ethoxy]-benzo...)
Affinity DataIC50:  140nMAssay Description:In vitro inhibition of human alphaV-beta5 integrin binding in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50161781(3-{6-[2-(6-Methylamino-pyridin-2-yl)-ethoxy]-benzo...)
Affinity DataIC50:  7.80E+3nMAssay Description:In vitro inhibition of human alpha5-beta1 integrin binding in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50161781(3-{6-[2-(6-Methylamino-pyridin-2-yl)-ethoxy]-benzo...)
Affinity DataIC50:  300nMAssay Description:In vitro inhibition of human alphaV-beta3 integrin binding in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed