BDBM50161782 3-{6-[2-(6-Methylamino-pyridin-2-yl)-ethoxy]-benzofuran-3-yl}-propionic acid::CHEMBL179400

SMILES CNc1cccc(CCOc2ccc3c(CCC(O)=O)coc3c2)n1

InChI Key InChIKey=XXGGOJFTDMPZAG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50161782   

TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50161782(3-{6-[2-(6-Methylamino-pyridin-2-yl)-ethoxy]-benzo...)
Affinity DataIC50: >2.00E+4nMAssay Description:In vitro inhibition of human alphaIIb betaIIIa integrin binding in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50161782(3-{6-[2-(6-Methylamino-pyridin-2-yl)-ethoxy]-benzo...)
Affinity DataIC50:  420nMAssay Description:In vitro inhibition of human alphaV-beta5 integrin binding in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50161782(3-{6-[2-(6-Methylamino-pyridin-2-yl)-ethoxy]-benzo...)
Affinity DataIC50: >2.00E+4nMAssay Description:In vitro inhibition of human alpha5-beta1 integrin binding in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50161782(3-{6-[2-(6-Methylamino-pyridin-2-yl)-ethoxy]-benzo...)
Affinity DataIC50:  330nMAssay Description:In vitro inhibition of human alphaV-beta3 integrin binding in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed