BDBM50161784 3-{5-[3-(Pyridin-2-ylamino)-propoxy]-indol-1-yl}-propionic acid::CHEMBL178859

SMILES OC(=O)CCn1ccc2cc(OCCCNc3ccccn3)ccc12

InChI Key InChIKey=AJDOOWNOWOSWPT-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50161784   

TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50161784(3-{5-[3-(Pyridin-2-ylamino)-propoxy]-indol-1-yl}-p...)
Affinity DataIC50: >2.00E+4nMAssay Description:In vitro inhibition of human alphaIIb betaIIIa integrin binding in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50161784(3-{5-[3-(Pyridin-2-ylamino)-propoxy]-indol-1-yl}-p...)
Affinity DataIC50:  470nMAssay Description:In vitro inhibition of human alphaV-beta3 integrin binding in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50161784(3-{5-[3-(Pyridin-2-ylamino)-propoxy]-indol-1-yl}-p...)
Affinity DataIC50:  2.5nMAssay Description:In vitro inhibition of human alphaV-beta5 integrin binding in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50161784(3-{5-[3-(Pyridin-2-ylamino)-propoxy]-indol-1-yl}-p...)
Affinity DataIC50:  40nMAssay Description:Inhibition of integrin alphavbeta5 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50161784(3-{5-[3-(Pyridin-2-ylamino)-propoxy]-indol-1-yl}-p...)
Affinity DataIC50:  470nMAssay Description:Inhibitory concentration against alphaV-beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50161784(3-{5-[3-(Pyridin-2-ylamino)-propoxy]-indol-1-yl}-p...)
Affinity DataIC50:  251nMAssay Description:Inhibition of integrin alphavbeta3 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50161784(3-{5-[3-(Pyridin-2-ylamino)-propoxy]-indol-1-yl}-p...)
Affinity DataIC50: >2.00E+4nMAssay Description:In vitro inhibition of human alpha5-beta1 integrin binding in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed