BDBM50161879 4-Dimethylamino-but-2-enoic acid {4-[3-chloro-4-(3-chloro-benzyloxy)-phenylamino]-3-cyano-7-ethoxy-quinolin-6-yl}-amide::CHEMBL179363::N-(4-(4-(3-chlorobenzyloxy)-3-chlorophenylamino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide
SMILES CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4cccc(Cl)c4)c(Cl)c3)c2cc1NC(=O)\C=C\CN(C)C
InChI Key InChIKey=XRZUOLFZBNANGA-RMKNXTFCSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50161879
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
University Of Southern California
Curated by ChEMBL
University Of Southern California
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of HER2 (unknown origin)More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
University Of Southern California
Curated by ChEMBL
University Of Southern California
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of human epidermal growth factor receptor-2 (HER-2) autophosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of human epidermal growth factor receptor (EGFR) autophosphorylationMore data for this Ligand-Target Pair