BDBM50163476 CHEMBL3792516

SMILES Cn1c(nc2ccc(cc12)-n1ccc(OCc2ccc(Cl)s2)cc1=O)C1CC1

InChI Key InChIKey=RPFBZAHRSRZYGF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50163476   

TargetMelanin-concentrating hormone receptor 1(RAT)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50163476(CHEMBL3792516)
Affinity DataIC50:  11nMAssay Description:Displacement of [125I]-MCH(4-19) from rat MCHR1 expressed in CHO cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50163476(CHEMBL3792516)
Affinity DataIC50:  19nMAssay Description:Displacement of [125I]-MCH(4 to 19) from human MCHR1 expressed in CHO cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50163476(CHEMBL3792516)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ERG by patch clamp testMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50163476(CHEMBL3792516)
Affinity DataIC50:  24nMAssay Description:Antagonist activity at human MCHR1 expressed in CHO cells assessed as change in MCH(4 to 19)-stimulated Ca2+ concentration by Ca2+ mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed