BDBM50163656 1-{(1R,2S)-2-[(S)-3-(4-Fluoro-benzyl)-piperidin-1-ylmethyl]-cyclohexyl}-3-[3-(5-methyl-tetrazol-1-yl)-phenyl]-urea::CHEMBL195555
SMILES Cc1nnnn1-c1cccc(NC(=O)N[C@@H]2CCCC[C@H]2CN2CCC[C@@H](Cc3ccc(F)cc3)C2)c1
InChI Key InChIKey=QLTHBTHVYYXPHB-VMODYCNZSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50163656
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of calcium mobilization in human eosinophilsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of eotaxin-induced chemotaxis of human eosinophilsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of [125I]eotaxin binding to human C-C chemokine receptor type 3 expressed in CHO cellsMore data for this Ligand-Target Pair