BDBM50164017 CHEMBL183544::N-[6-Cyano-1-(3-methyl-3H-imidazol-4-ylmethyl)-1,2,3,4-tetrahydro-quinolin-3-yl]-N-(2-methyl-allyl)-benzenesulfonamide

SMILES CC(=C)CN(C1CN(Cc2cncn2C)c2ccc(cc2C1)C#N)S(=O)(=O)c1ccccc1

InChI Key InChIKey=GSZHIOCIMUCGFD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50164017   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50164017(CHEMBL183544 | N-[6-Cyano-1-(3-methyl-3H-imidazol-...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of human farnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed