BDBM50164020 CHEMBL180710::N-Benzyl-N-[6-cyano-1-(3-methyl-3H-imidazol-4-ylmethyl)-1,2,3,4-tetrahydro-quinolin-3-yl]-benzenesulfonamide

SMILES Cn1cncc1CN1CC(Cc2cc(ccc12)C#N)N(Cc1ccccc1)S(=O)(=O)c1ccccc1

InChI Key InChIKey=HLZAMOBHOGVCHD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50164020   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50164020(CHEMBL180710 | N-Benzyl-N-[6-cyano-1-(3-methyl-3H-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human farnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed