BDBM50164025 BMS-316810::CHEMBL360330::Pyridine-2-sulfonic acid [6-cyano-1-(3-methyl-3H-imidazol-4-ylmethyl)-1,2,3,4-tetrahydro-quinolin-3-yl]-thiophen-3-ylmethyl-amide

SMILES Cn1cncc1CN1CC(Cc2cc(ccc12)C#N)N(Cc1ccsc1)S(=O)(=O)c1ccccn1

InChI Key InChIKey=FPEPZFNRGIPRRN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50164025   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50164025(BMS-316810 | CHEMBL360330 | Pyridine-2-sulfonic ac...)
Affinity DataIC50:  13nMAssay Description:Inhibition of cellular reversion in H-ras transformed Rat-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50164025(BMS-316810 | CHEMBL360330 | Pyridine-2-sulfonic ac...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of human farnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed