BDBM50164033 CHEMBL183380::N-[2,2'']Bithiophenyl-5-ylmethyl-N''-(2''-sulfamoyl-biphenyl-4-ylmethyl)-isophthalamide

SMILES NS(=O)(=O)c1ccccc1-c1ccc(CNC(=O)c2cccc(c2)C(=O)NCc2ccc(s2)-c2cccs2)cc1

InChI Key InChIKey=NMONGYGAHGGEGU-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50164033   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164033(CHEMBL183380 | N-[2,2'']Bithiophenyl-5-ylmethyl-N'...)
Affinity DataKi:  6.20E+3nMAssay Description:Inhibitory constant against voltage-gated sodium channel Nav1.7 in electrophysiology assays (EP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164033(CHEMBL183380 | N-[2,2'']Bithiophenyl-5-ylmethyl-N'...)
Affinity DataIC50:  2.90E+3nMAssay Description:In vitro inhibitory concentration against voltage-gated sodium channel Nav1.7 in voltage-ion-probe-reader (VIPR) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed