BDBM50164473 2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-(3-fluoro-propyl)-phenylamine::CHEMBL363396::N-(2-{[2-amino-4-(3-fluoropropyl)phenyl]thio}benzyl)-N,N-dimethylamine

SMILES CN(C)Cc1ccccc1Sc1ccc(CCCF)cc1N

InChI Key InChIKey=WTJNBQYUXJFISF-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50164473   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50164473(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-(3-fluo...)
Affinity DataKi:  3.58nMAssay Description:In vitro displacement of [3H]-paroxetine from human serotonin transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons

Curated by ChEMBL
LigandPNGBDBM50164473(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-(3-fluo...)
Affinity DataKi:  8.55nMAssay Description:In vitro inhibition of [3H]-citalopram binding to human serotonin transporter expressed in human HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50164473(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-(3-fluo...)
Affinity DataKi:  219nMAssay Description:In vitro inhibition of [3H]-nisoxetine binding to norepinephrine transporter expressed in human kidney cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50164473(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-(3-fluo...)
Affinity DataKi:  505nMAssay Description:In vitro displacement of [3H]-nisoxetine from human norepinephrine transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50164473(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-(3-fluo...)
Affinity DataKi: >5.00E+3nMAssay Description:In vitro inhibition of [3H]-WIN- 35,428 binding to human dopamine transporter expressed in canine kidney cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50164473(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-(3-fluo...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro displacement of [3H]-GBR-12,935 from human dopamine transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed