BDBM50164528 CHEMBL3799183
SMILES ONC(=O)c1ccc(Cl)c(NC(=O)c2ccc(Oc3ccccc3)cc2)c1
InChI Key InChIKey=CNGUERNKNNKCCR-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50164528
TargetHistone deacetylase 1(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of recombinant human HDAC1 using Cbz-(Ac)Lys-AMC as substrate preincubated for 90 mins followed by trypsin addition measured after 20 mins...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of recombinant human HDAC8 using Fluor de Lys as substrate preincubated for 90 mins followed by BML-KI176 addition measured after 45 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 977nMAssay Description:Inhibition of Schistosoma mansoni KDAC8 using (FAM)-labeled peptide as substrate after 60 mins by microfluidic assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Martin-Luther University Of Halle-Wittenberg
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant human HDAC6 using Cbz-(Ac)Lys-AMC as substrate preincubated for 90 mins followed by trypsin addition measured after 20 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 979nMAssay Description:Inhibition of recombinant Schistosoma mansoni HDAC8 expressed in Escherichia coli using Fluor de Lys as substrate preincubated for 90 mins followed b...More data for this Ligand-Target Pair