BDBM50164704 CHEMBL364935::N*4*-(3H-Benzoimidazol-5-yl)-N*2*-(4-bromo-phenyl)-5-trifluoromethyl-pyrimidine-2,4-diamine

SMILES FC(F)(F)c1cnc(Nc2ccc(Br)cc2)nc1Nc1ccc2nc[nH]c2c1

InChI Key InChIKey=LSGWJMLNFPIPPC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50164704   

TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50164704(CHEMBL364935 | N*4*-(3H-Benzoimidazol-5-yl)-N*2*-(...)
Affinity DataIC50:  260nMAssay Description:Inhibitory concentration against Cyclin dependent kinase 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50164704(CHEMBL364935 | N*4*-(3H-Benzoimidazol-5-yl)-N*2*-(...)
Affinity DataIC50:  260nMAssay Description:Inhibitory concentration against Cyclin dependent kinase 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50164704(CHEMBL364935 | N*4*-(3H-Benzoimidazol-5-yl)-N*2*-(...)
Affinity DataIC50:  11nMAssay Description:Inhibitory concentration against Cyclin dependent kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50164704(CHEMBL364935 | N*4*-(3H-Benzoimidazol-5-yl)-N*2*-(...)
Affinity DataIC50:  750nMAssay Description:Inhibitory concentration against Extracellular signal-regulated kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed