BDBM50164849 CHEMBL3800633
SMILES CN(CCCCNC(=O)c1cc2ccccc2o1)[C@@H]1Cc2cccc3[nH]c(=O)n(C1)c23
InChI Key InChIKey=FGHOMVBEDZJTLR-GOSISDBHSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50164849
TargetD(2) dopamine receptor(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Displacement of [3H]7-OH-DPAT from human D2 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataKi: 256nMAssay Description:Displacement of [3H]7-OH-DPAT from human D3 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataKi: 2.61E+3nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataKi: 1.47E+4nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataEC50: 163nMAssay Description:Agonist activity at human dopamine D2 receptor expressed in HEK293 cells coexpressing renilla luciferase-fused Galphai1/GFP10-fused Ggamma2 by BRET a...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataEC50: 78nMAssay Description:Binding affinity against progesterone receptor using human T47D breast carcinoma cell lineMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataEC50: 66nMAssay Description:Agonist activity at human dopamine D2 receptor expressed in HEK293 cells assessed as cAMP inhibition by BRET assayMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataEC50: 20nMAssay Description:Agonist activity at recombinant human D3 receptor expressing in CHOp cells assessed as receptor mediated stimulation of mitogenesis measured as [3H]t...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataEC50: 210nMAssay Description:Agonist activity at renilla luciferase-tagged human dopamine D2 receptor expressed in HEK293 cells coexpressing mVenus-fused beta-arrestin 2 assessed...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataEC50: 115nMAssay Description:Agonist activity at human D3 receptor transfected in HEK293T cells by BRET based G0 activation assayMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataEC50: 43nMAssay Description:Agonist activity at human D2 receptor transfected in HEK293T cells by BRET based G0 activation assayMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataEC50: 20nMAssay Description:Agonist activity at recombinant human D2 receptor expressing in CHOp cells assessed as receptor mediated stimulation of mitogenesis measured as [3H]t...More data for this Ligand-Target Pair