BDBM50165296 9-(2-Isopropoxy-ethyl)-8-(3-methoxy-benzenesulfonyl)-9H-purin-6-ylamine::CHEMBL362972

SMILES COc1cccc(c1)S(=O)(=O)c1nc2c(N)ncnc2n1CCOC(C)C

InChI Key InChIKey=FHYGDELHNKRLBR-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50165296   

TargetHeat shock protein HSP 90-alpha(Mus musculus)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50165296(9-(2-Isopropoxy-ethyl)-8-(3-methoxy-benzenesulfony...)
Affinity DataEC50: >5.00E+4nMAssay Description:Displacement of 5 nM GM-BODIPY from mouse heat shock protein HSP90-alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50165296(9-(2-Isopropoxy-ethyl)-8-(3-methoxy-benzenesulfony...)
Affinity DataIC50:  1.70E+5nMAssay Description:Inhibition of Hsp90 protein as degradation of HER2 kinase in SKBr3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed