BDBM50165313 8-(2,4-Dichloro-5-methoxy-phenylsulfanyl)-9-(2-isopropoxy-ethyl)-9H-purin-6-ylamine::CHEMBL363196::US10676476, Example 3
SMILES COc1cc(Sc2nc3c(N)ncnc3n2CCOC(C)C)c(Cl)cc1Cl
InChI Key InChIKey=VJHQQVOFWCXUBZ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50165313
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataIC50: 5.83E+4nMAssay Description:Inhibition of Hsp90 protein as degradation of HER2 kinase in SKBr3 cellsMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Sloan-Kettering Institute For Cancer Research
US Patent
Sloan-Kettering Institute For Cancer Research
US Patent
Affinity DataIC50: 5.83E+4nMAssay Description:The biochemical assay tests competitive binding of compounds to recombinant Hsp90α protein and also Hsp90 found in cell specific complexes, and ...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Sloan-Kettering Institute For Cancer Research
US Patent
Sloan-Kettering Institute For Cancer Research
US Patent
Affinity DataEC50: 5.00E+3nMAssay Description:The biochemical assay tests competitive binding of compounds to recombinant Hsp90α protein and also Hsp90 found in cell specific complexes, and ...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Mus musculus)
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Memorial Sloan-Kettering Cancer Center
Curated by ChEMBL
Affinity DataEC50: 5.00E+3nMAssay Description:Displacement of 5 nM GM-BODIPY from mouse heat shock protein HSP90-alphaMore data for this Ligand-Target Pair