BDBM50165584 CHEMBL3798056

SMILES COc1ccc(Cn2c(nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(C)=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](N)CCCCN)cc1

InChI Key InChIKey=RZBIQVZXTUBILW-HKWZHHDHSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50165584   

TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM50165584(CHEMBL3798056)
Affinity DataKi:  3nMAssay Description:Binding affinity at GHS-R1a (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM50165584(CHEMBL3798056)
Affinity DataKi:  110nM ΔG°:  -9.49kcal/moleT: 2°CAssay Description:Competitive binding affinity to human SNAP-tagged GHS-R1a expressed in HEK293T cells incubated at 4 degC for 3 hrs or at room temperature for 1 hr by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM50165584(CHEMBL3798056)
Affinity DataEC50:  70nMAssay Description:Inverse agonist activity at GHS-R1a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM50165584(CHEMBL3798056)
Affinity DataEC50:  70nMAssay Description:Inverse agonist activity at human GHS-R1a expressed in HEK293T cells after 45 mins by HTRF-based IP3 turnover assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed