BDBM50165799 (R)-1-{4-[3-(2-Methoxy-benzyloxy)-propoxy]-phenyl}-6-(1,2,3,4-tetrahydro-quinolin-7-yloxymethyl)-piperazin-2-one::CHEMBL195983

SMILES COc1ccccc1COCCCOc1ccc(cc1)N1[C@@H](COc2ccc3CCCNc3c2)CNCC1=O

InChI Key InChIKey=JXFXZCANEQOOHW-AREMUKBSSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50165799   

TargetRenin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50165799((R)-1-{4-[3-(2-Methoxy-benzyloxy)-propoxy]-phenyl}...)
Affinity DataIC50:  120nMAssay Description:Concentration required to inhibit renin activity by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed