BDBM50165819 7-Benzyl-4,9-dimethyl-2-phenyl-7H-3,3a,5,7,8-pentaaza-cyclopenta[a]naphthalen-6-one::CHEMBL382494

SMILES Cc1nn(Cc2ccccc2)c(=O)c2nc(C)n3nc(cc3c12)-c1ccccc1

InChI Key InChIKey=GKMOVBXNXJHZPK-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50165819   

TargetAdenosine receptor A1(Homo sapiens (Human))
Dipartimento Di Scienze Farmaceutiche

Curated by ChEMBL
LigandPNGBDBM50165819(7-Benzyl-4,9-dimethyl-2-phenyl-7H-3,3a,5,7,8-penta...)
Affinity DataKi:  3.25E+3nMAssay Description:Binding affinity to human adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Dipartimento Di Scienze Farmaceutiche

Curated by ChEMBL
LigandPNGBDBM50165819(7-Benzyl-4,9-dimethyl-2-phenyl-7H-3,3a,5,7,8-penta...)
Affinity DataIC50:  160nMAssay Description:Inhibition of human platelets PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Dipartimento Di Scienze Farmaceutiche

Curated by ChEMBL
LigandPNGBDBM50165819(7-Benzyl-4,9-dimethyl-2-phenyl-7H-3,3a,5,7,8-penta...)
Affinity DataIC50:  160nMAssay Description:Inhibition of human Phosphodiesterase 5 (n=2-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Dipartimento Di Scienze Farmaceutiche

Curated by ChEMBL
LigandPNGBDBM50165819(7-Benzyl-4,9-dimethyl-2-phenyl-7H-3,3a,5,7,8-penta...)
Affinity DataIC50:  160nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed