BDBM50165929 Ac-YR[CEH(pCl-dF)RWC]-NH2::CHEMBL415661

SMILES CC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]1CSSC[C@@H](NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc2ccc(Cl)cc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@@H](CCC(O)=O)NC1=O)C(N)=O

InChI Key InChIKey=KIFNALNSUOJQPJ-XVRHLUALSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50165929   

TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165929(Ac-YR[CEH(pCl-dF)RWC]-NH2 | CHEMBL415661)
Affinity DataKi:  0.140nMAssay Description:Inhibition of [125I]-NDP-alpha-MSH binding to melanocortin-4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165929(Ac-YR[CEH(pCl-dF)RWC]-NH2 | CHEMBL415661)
Affinity DataKi:  3.10nMAssay Description:Inhibition of [125I]-NDP-alpha-MSH binding to melanocortin-3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165929(Ac-YR[CEH(pCl-dF)RWC]-NH2 | CHEMBL415661)
Affinity DataKi:  8.20nMAssay Description:Inhibition of [125I]NDP-alpha-MSH binding to melanocortin-1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165929(Ac-YR[CEH(pCl-dF)RWC]-NH2 | CHEMBL415661)
Affinity DataKi:  42nMAssay Description:Inhibition of [125I]NDP-alpha-MSH binding to melanocortin-5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165929(Ac-YR[CEH(pCl-dF)RWC]-NH2 | CHEMBL415661)
Affinity DataEC50:  0.0600nMAssay Description:Agonist activity at human Melanocortin-4 receptor as peptide required for 50% maximal cAMP release (n > or =2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed