BDBM50166497 1,2-Bis-(4-chloro-phenyl)-4-[4-(4-fluoro-phenyl)-4-oxo-butyl]-pyrazolidine-3,5-dione::CHEMBL370034

SMILES Oc1c(CCCC(=O)c2ccc(F)cc2)c(=O)n(-c2ccc(Cl)cc2)n1-c1ccc(Cl)cc1

InChI Key InChIKey=VCBGYZYQHOUKNW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50166497   

TargetUDP-N-acetylenolpyruvoylglucosamine reductase(Escherichia coli K-12 (Enterobacteria))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50166497(1,2-Bis-(4-chloro-phenyl)-4-[4-(4-fluoro-phenyl)-4...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibitory concentration against MurB enzyme in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylenolpyruvoylglucosamine reductase(Staphylococcus aureus (Firmicutes))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50166497(1,2-Bis-(4-chloro-phenyl)-4-[4-(4-fluoro-phenyl)-4...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibitory concentration against MurB enzyme in Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylglucosamine 1-carboxyvinyltransferase(Escherichia coli K-12 (Enterobacteria))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50166497(1,2-Bis-(4-chloro-phenyl)-4-[4-(4-fluoro-phenyl)-4...)
Affinity DataIC50:  3.24E+4nMAssay Description:Inhibitory concentration against MurA enzyme in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed