BDBM50166704 1-{1-[(4-chlorophenyl)sulfonyl]cyclohexyl}-2-fluorobenzene::CHEMBL191246
SMILES Fc1ccccc1C1(CCCCC1)S(=O)(=O)c1ccc(Cl)cc1
InChI Key InChIKey=MLQCGTIQCWRFKG-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50166704
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:In vitro inhibition of gamma-secretase as amyloid peptide production in SH-SY5Y cellsMore data for this Ligand-Target Pair