BDBM50166709 4-(4-Chloro-benzenesulfonyl)-4-(2,5-difluoro-phenyl)-cyclohexanone::CHEMBL366022

SMILES Fc1ccc(F)c(c1)C1(CCC(=O)CC1)S(=O)(=O)c1ccc(Cl)cc1

InChI Key InChIKey=MABHMOXKRMWJGK-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50166709   

TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL

LigandBDBM50166709(4-(4-Chloro-benzenesulfonyl)-4-(2,5-difluoro-pheny...)Copy SMILESCopy InChI

Affinity DataIC50:  22nMAssay Description:In vitro inhibition of gamma-secretase as amyloid peptide production in SH-SY5Y cellsMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
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Ligand InfoPurchaseCHEMBLPC cidPC sidPatentsSimilars

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