BDBM50166711 2-((4-chlorophenylsulfonyl)methyl)-1,4-difluorobenzene::2-(4-Chloro-benzenesulfonylmethyl)-1,4-difluoro-benzene::CHEMBL194820
SMILES Fc1ccc(F)c(CS(=O)(=O)c2ccc(Cl)cc2)c1
InChI Key InChIKey=HHEQSSURHUQFCS-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50166711
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 4.41E+3nMAssay Description:In vitro inhibition of gamma-secretase as amyloid peptide production in SH-SY5Y cellsMore data for this Ligand-Target Pair