BDBM50166714 1-Chloro-4-(1-phenyl-cyclohexanesulfonyl)-benzene::CHEMBL191195
SMILES Clc1ccc(cc1)S(=O)(=O)C1(CCCCC1)c1ccccc1
InChI Key InChIKey=XMYNJSLMUBGZIQ-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50166714
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 461nMAssay Description:In vitro inhibition of gamma-secretase as amyloid peptide production in SH-SY5Y cellsMore data for this Ligand-Target Pair