BDBM50167327 CHEMBL191045::[4-Chloro-6-(4-sulfamoyl-benzylamino)-[1,3,5]triazin-2-ylamino]-acetic acid

SMILES NS(=O)(=O)c1ccc(CNc2nc(Cl)nc(NCC(O)=O)n2)cc1

InChI Key InChIKey=HGULMEYATWWKDO-UHFFFAOYSA-N

Data  14 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50167327   

TargetCarbonic anhydrase 9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50167327(CHEMBL191045 | [4-Chloro-6-(4-sulfamoyl-benzylamin...)
Affinity DataKi:  1.70nMAssay Description:Inhibitory constant against human Carbonic anhydrase IXMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50167327(CHEMBL191045 | [4-Chloro-6-(4-sulfamoyl-benzylamin...)
Affinity DataKi:  7.90nMAssay Description:Inhibition of human recombinant carbonic anhydrase 9 preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50167327(CHEMBL191045 | [4-Chloro-6-(4-sulfamoyl-benzylamin...)
Affinity DataKi:  9.30nMAssay Description:Inhibition of human recombinant carbonic anhydrase 14 preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50167327(CHEMBL191045 | [4-Chloro-6-(4-sulfamoyl-benzylamin...)
Affinity DataKi:  9.40nMAssay Description:Inhibition of human recombinant carbonic anhydrase 7 preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50167327(CHEMBL191045 | [4-Chloro-6-(4-sulfamoyl-benzylamin...)
Affinity DataKi:  10.2nMAssay Description:Inhibition of human recombinant carbonic anhydrase 12 preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50167327(CHEMBL191045 | [4-Chloro-6-(4-sulfamoyl-benzylamin...)
Affinity DataKi:  24nMAssay Description:Inhibition of human recombinant carbonic anhydrase 5b preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50167327(CHEMBL191045 | [4-Chloro-6-(4-sulfamoyl-benzylamin...)
Affinity DataKi:  29nMAssay Description:Inhibitory constant against human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50167327(CHEMBL191045 | [4-Chloro-6-(4-sulfamoyl-benzylamin...)
Affinity DataKi:  35nMAssay Description:Inhibitory constant against human Carbonic anhydrase IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5A, mitochondrial(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50167327(CHEMBL191045 | [4-Chloro-6-(4-sulfamoyl-benzylamin...)
Affinity DataKi:  48nMAssay Description:Inhibition of human recombinant carbonic anhydrase 5a preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50167327(CHEMBL191045 | [4-Chloro-6-(4-sulfamoyl-benzylamin...)
Affinity DataKi:  59nMAssay Description:Inhibition of human recombinant carbonic anhydrase 6 preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 13(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50167327(CHEMBL191045 | [4-Chloro-6-(4-sulfamoyl-benzylamin...)
Affinity DataKi:  62nMAssay Description:Inhibition of human recombinant carbonic anhydrase 13 preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50167327(CHEMBL191045 | [4-Chloro-6-(4-sulfamoyl-benzylamin...)
Affinity DataKi:  89nMAssay Description:Inhibition of human recombinant carbonic anhydrase 4 preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50167327(CHEMBL191045 | [4-Chloro-6-(4-sulfamoyl-benzylamin...)
Affinity DataKi:  351nMAssay Description:Inhibition of human recombinant cytosolic carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50167327(CHEMBL191045 | [4-Chloro-6-(4-sulfamoyl-benzylamin...)
Affinity DataKi:  3.03E+3nMAssay Description:Inhibition of human recombinant cytosolic carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed