BDBM50167465 4,6-dioxa-14-azatetracyclo[10.3.1.02,10.03,7]hexadeca-2,7,9-triene::CHEMBL373359

SMILES C1Oc2ccc3CC4CNCC(C4)c3c2O1

InChI Key InChIKey=JCOOLTXCASTQDG-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50167465   

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50167465(4,6-dioxa-14-azatetracyclo[10.3.1.02,10.03,7]hexad...)
Affinity DataKi:  5.70nMAssay Description:Binding affinity against nicotinic acetylcholine receptor alpha4-beta2 in human HEK293 cells using [3H]- nicotine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50167465(4,6-dioxa-14-azatetracyclo[10.3.1.02,10.03,7]hexad...)
Affinity DataKi:  5.10E+3nMAssay Description:Inhibition of [3H]alpha-bungarotoxin binding to nicotinic acetylcholine receptor alpha7 of IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed