BDBM50167808 1-(4-fluorophenyl)-4a-methyl-(4aS)-spiro[4,4a,5,6,7,8-hexahydro-1H-benzo[f]indazole-5,2'-(dihydro[1,3]dioxolane)]::CHEMBL196509

SMILES C[C@]12Cc3cnn(c3C=C1CCCC21OCCO1)-c1ccc(F)cc1

InChI Key InChIKey=QVHBWRWKGYSOAM-IBGZPJMESA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50167808   

TargetGlucocorticoid receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50167808(1-(4-fluorophenyl)-4a-methyl-(4aS)-spiro[4,4a,5,6,...)
Affinity DataIC50:  14nMAssay Description:Binding affinity for human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(RAT)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50167808(1-(4-fluorophenyl)-4a-methyl-(4aS)-spiro[4,4a,5,6,...)
Affinity DataIC50:  7.56E+3nMAssay Description:Binding affinity for rat mineralocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50167808(1-(4-fluorophenyl)-4a-methyl-(4aS)-spiro[4,4a,5,6,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity for human estrogen receptor betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50167808(1-(4-fluorophenyl)-4a-methyl-(4aS)-spiro[4,4a,5,6,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity for human estrogen receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50167808(1-(4-fluorophenyl)-4a-methyl-(4aS)-spiro[4,4a,5,6,...)
Affinity DataIC50: >1.00E+3nMAssay Description:Binding affinity for human progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50167808(1-(4-fluorophenyl)-4a-methyl-(4aS)-spiro[4,4a,5,6,...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human glucocorticoid receptor alpha isoform More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed