BDBM50167877 CHEMBL3798081

SMILES CC(C)(C#N)c1cccc(c1)C(=O)Nc1cccc(Nc2ccnc(NC(=O)C3CC3)c2)c1

InChI Key InChIKey=JWVFWAOUTZYRSM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50167877   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Jilin University

Curated by ChEMBL
LigandPNGBDBM50167877(CHEMBL3798081)
Affinity DataIC50:  38nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged B-Raf V600E mutant expressed in baculovirus expression system using Z'-LYTE Ser/Thr3 peptide as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Jilin University

Curated by ChEMBL
LigandPNGBDBM50167877(CHEMBL3798081)
Affinity DataIC50:  476nMAssay Description:Inhibition of recombinant wild type full length human GST-tagged B-Raf expressed in baculovirus expression system using Z'-LYTE Ser/Thr3 peptide as s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed