BDBM50167935 CHEMBL195083::N-{4-[4-(3-chloro-2-methoxyphenyl)piperazin-1-yl]butyl}-1-ferra-1,1'-spirobi[pentacyclo[2.2.0.0^{1,3}.0^{1,5}.0^{2,6}]hexane]-2,2',4,4'-tetraene-6-carboxamide

SMILES c1(Cl)c(c(N2CCN(CC2)CCCCNC(C23[Fe]456789%10%11C%12C4=C5C6=C7%12)=O)ccc1)OC.C8(C9=C2%10)=C3%11

InChI Key InChIKey=RKIAQJFOXBVIPS-UHFFFAOYSA-N

Data  6 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50167935   

TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50167935(CHEMBL195083 | N-{4-[4-(3-chloro-2-methoxyphenyl)p...)
Affinity DataKi:  0.910nMAssay Description:Inhibition of [3H]spiperone binding to human dopamine receptor D4.4 expressed in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50167935(CHEMBL195083 | N-{4-[4-(3-chloro-2-methoxyphenyl)p...)
Affinity DataKi:  3.5nMAssay Description:Inhibition of [3H]spiperone binding to human dopamine receptor D3 expressed in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50167935(CHEMBL195083 | N-{4-[4-(3-chloro-2-methoxyphenyl)p...)
Affinity DataKi:  14nMAssay Description:Binding affinity towards porcine serotonin receptor 5-HT1A using [3H]8-OH-DPATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50167935(CHEMBL195083 | N-{4-[4-(3-chloro-2-methoxyphenyl)p...)
Affinity DataKi:  72nMAssay Description:Inhibition of [3H]spiperone binding to human dopamine receptor D2 short expressed in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50167935(CHEMBL195083 | N-{4-[4-(3-chloro-2-methoxyphenyl)p...)
Affinity DataKi:  99nMAssay Description:Inhibition of [3H]spiperone binding to human dopamine receptor D2 long expressed in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Sus scrofa)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50167935(CHEMBL195083 | N-{4-[4-(3-chloro-2-methoxyphenyl)p...)
Affinity DataKi:  2.20E+3nMAssay Description:Inhibition of [3H]-SCH- 23390 binding to dopamine receptor D1 of porcine striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50167935(CHEMBL195083 | N-{4-[4-(3-chloro-2-methoxyphenyl)p...)
Affinity DataEC50:  23nMAssay Description:Effective concentration for [35S]GTP-gamma-S, binding in CHO-K1 cells expressing human dopamine D4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50167935(CHEMBL195083 | N-{4-[4-(3-chloro-2-methoxyphenyl)p...)
Affinity DataEC50:  9.80nMAssay Description:Effective concentration in [3H]thymidine uptake assay by CHO dhfr- mutant cells expressing human D3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50167935(CHEMBL195083 | N-{4-[4-(3-chloro-2-methoxyphenyl)p...)
Affinity DataEC50:  22nMAssay Description:Effective concentration from [3H]thymidine uptake assay in CHO10001 cells expressing human Dopamine receptor D4.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed