BDBM50168081 CHEMBL3799802::MK 0893

SMILES COc1ccc2cc(ccc2c1)-c1cc(nn1C(C)c1ccc(cc1)C(=O)NCCC(O)=O)-c1cc(Cl)cc(Cl)c1

InChI Key InChIKey=DNTVJEMGHBIUMW-UHFFFAOYSA-N

Data  5 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50168081   

TargetGlucagon receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50168081(CHEMBL3799802 | MK 0893)
Affinity DataIC50:  50nMAssay Description:Displacement of [125I]-glucagon from wild type human glucagon receptor expressed in CHOK1 cells after 3 hrs by micro beta scintillation counting anal...More data for this Ligand-Target Pair
TargetGlucagon receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50168081(CHEMBL3799802 | MK 0893)
Affinity DataIC50:  100nMAssay Description:Antagonist activity at human glucagon receptor expressed in HEK293T cells assessed as inhibition of glucagon-induced cAMP accumulation after 30 mins ...More data for this Ligand-Target Pair