BDBM50168482 CHEMBL3805302

SMILES C[C@H](Nc1ccncn1)c1nc2cccc(Cl)c2c(=O)n1-c1ccccc1

InChI Key InChIKey=GKRKBAUXKMGSPH-ZDUSSCGKSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50168482   

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL

LigandBDBM50168482(CHEMBL3805302)Copy SMILESCopy InChI

Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition human full length PI3Kdelta catalytic subunit/p85alpha assessed as formation of PIP3 after 30 mins by europium labeled GRP-based TR-FRET a...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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