BDBM50168741 (2R,3R)-1-[4-(4-Fluoro-2-methyl-benzyloxy)-benzenesulfonyl]-3-hydroxy-3-methyl-piperidine-2-carboxylic acid hydroxyamide::CHEMBL365283

SMILES Cc1cc(F)ccc1COc1ccc(cc1)S(=O)(=O)N1CCC[C@@](C)(O)[C@@H]1C(=O)NO

InChI Key InChIKey=ZHCXOELPVFPGHI-PZJWPPBQSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50168741   

LigandPNGBDBM50168741((2R,3R)-1-[4-(4-Fluoro-2-methyl-benzyloxy)-benzene...)
Affinity DataIC50:  2.5nMAssay Description:Inhibitory concentration against TNF-alpha release in LPS treated whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50168741((2R,3R)-1-[4-(4-Fluoro-2-methyl-benzyloxy)-benzene...)
Affinity DataIC50:  219nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50168741((2R,3R)-1-[4-(4-Fluoro-2-methyl-benzyloxy)-benzene...)
Affinity DataIC50:  220nMAssay Description:Inhibitory concentration against MMP-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50168741((2R,3R)-1-[4-(4-Fluoro-2-methyl-benzyloxy)-benzene...)
Affinity DataIC50:  15nMAssay Description:Inhibitory concentration of the compound against rat TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed