BDBM50168988 (2R,3R,4S)-2-({[(1R)-2-HYDROXY-1-PHENYLETHYL]AMINO}METHYL)PYRROLIDINE-3,4-DIOL::CHEMBL425723

SMILES OC[C@H](NC[C@H]1NC[C@H](O)[C@@H]1O)c1ccccc1

InChI Key InChIKey=OGMKEJTXCCFISS-MROQNXINSA-N

Data  7 KI  5 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50168988   

Targetalpha-1,2-Mannosidase(Glycine max)
Institute Of Chemical Sciences And Engineering

Curated by ChEMBL
LigandPNGBDBM50168988((2R,3R,4S)-2-({[(1R)-2-HYDROXY-1-PHENYLETHYL]AMINO...)
Affinity DataKi:  135nMAssay Description:Binding affinity towards alpha-Mannosidase isolated from Jack beanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetalpha-1,2-Mannosidase(Glycine max)
Institute Of Chemical Sciences And Engineering

Curated by ChEMBL
LigandPNGBDBM50168988((2R,3R,4S)-2-({[(1R)-2-HYDROXY-1-PHENYLETHYL]AMINO...)
Affinity DataKi:  9.50E+3nMAssay Description:Binding affinity towards alpha-Mannosidase isolated from AlmondMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase(Homo sapiens (Human))
Universidade Do Porto 687

Curated by ChEMBL
LigandPNGBDBM50168988((2R,3R,4S)-2-({[(1R)-2-HYDROXY-1-PHENYLETHYL]AMINO...)
Affinity DataKi:  1.68E+4nMAssay Description:Inhibition of human ER alpha mannosidase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique FéDéRale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50168988((2R,3R,4S)-2-({[(1R)-2-HYDROXY-1-PHENYLETHYL]AMINO...)
Affinity DataKi:  2.33E+4nMAssay Description:Inhibition of alpha-mannosidase in human HCECMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-mannosidase 2(Homo sapiens (Human))
Universidade Do Porto 687

Curated by ChEMBL
LigandPNGBDBM50168988((2R,3R,4S)-2-({[(1R)-2-HYDROXY-1-PHENYLETHYL]AMINO...)
Affinity DataKi:  2.69E+4nMAssay Description:Inhibition of human golgi alpha mannosidase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique FéDéRale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50168988((2R,3R,4S)-2-({[(1R)-2-HYDROXY-1-PHENYLETHYL]AMINO...)
Affinity DataKi:  3.25E+4nMAssay Description:Inhibition of alpha-mannosidase in human LN18 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique FéDéRale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50168988((2R,3R,4S)-2-({[(1R)-2-HYDROXY-1-PHENYLETHYL]AMINO...)
Affinity DataKi:  4.15E+4nMAssay Description:Inhibition of alpha-mannosidase in human LNZ308 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique FéDéRale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50168988((2R,3R,4S)-2-({[(1R)-2-HYDROXY-1-PHENYLETHYL]AMINO...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of alpha-mannosidase in human HCECMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique FéDéRale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50168988((2R,3R,4S)-2-({[(1R)-2-HYDROXY-1-PHENYLETHYL]AMINO...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of alpha-mannosidase in human LNZ308 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetalpha-1,2-Mannosidase(Glycine max)
Institute Of Chemical Sciences And Engineering

Curated by ChEMBL
LigandPNGBDBM50168988((2R,3R,4S)-2-({[(1R)-2-HYDROXY-1-PHENYLETHYL]AMINO...)
Affinity DataIC50:  700nMAssay Description:Concentration of compound inhibiting alpha-Mannosidase isolated from Jack beanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetalpha-1,2-Mannosidase(Glycine max)
Institute Of Chemical Sciences And Engineering

Curated by ChEMBL
LigandPNGBDBM50168988((2R,3R,4S)-2-({[(1R)-2-HYDROXY-1-PHENYLETHYL]AMINO...)
Affinity DataIC50:  4.60E+4nMAssay Description:Inhibition of alpha-Mannosidase isolated from almondMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-mannosidase(Homo sapiens (Human))
Ecole Polytechnique FéDéRale De Lausanne

Curated by ChEMBL
LigandPNGBDBM50168988((2R,3R,4S)-2-({[(1R)-2-HYDROXY-1-PHENYLETHYL]AMINO...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of alpha-mannosidase in human LN18 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed