BDBM50168995 (-)-swainsonine::(1S,2R,8R,8aR)-Octahydro-indolizine-1,2,8-triol::1S-8AB-OCTAHYDRO-INDOLIZIDINE-1A,2A,8B-TRIOL::CHEMBL371197::SWAINSONINE

SMILES O[C@@H]1CN2CCC[C@@H](O)[C@@H]2[C@@H]1O

InChI Key InChIKey=FXUAIOOAOAVCGD-WCTZXXKLSA-N

Data  4 KI  7 IC50

PDB links: 5 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50168995   

TargetAlpha-1,2-mannosidase, putative(Bacteroides thetaiotaomicron )
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50168995((-)-swainsonine | (1S,2R,8R,8aR)-Octahydro-indoliz...)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 3990 assessed as reduction of mannose release using 4NP-mannopyranoside substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1,2-mannosidase, putative(Bacteroides thetaiotaomicron )
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50168995((-)-swainsonine | (1S,2R,8R,8aR)-Octahydro-indoliz...)
Affinity DataKi:  1.40E+4nMAssay Description:Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 2199 assessed as reduction of mannose release using 4NP-mannopyranoside substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed