BDBM50169548 CHEMBL3805176
SMILES [H][C@]12C[C@@H](O)[C@H](\C=C\CCOc3ccccc3)[C@@]1([H])CC[C@@H](O2)c1nc(cs1)C(O)=O
InChI Key InChIKey=MQAJFAGHNPJXCS-UHFFFAOYSA-N
Data 7 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50169548
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Ono Pharmaceutical
Curated by ChEMBL
Ono Pharmaceutical
Curated by ChEMBL
Affinity DataEC50: 1.90E+3nMAssay Description:Agonist activity at human EP4 receptor expressed in CHO cells assessed as increase in intracellular cAMP level after 30 mins by HTRF methodMore data for this Ligand-Target Pair
Affinity DataEC50: 2.50E+3nMAssay Description:Agonist activity at human IP receptor expressed in CHO cells assessed as increase in intracellular cAMP level after 30 mins by HTRF methodMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ono Pharmaceutical
Curated by ChEMBL
Ono Pharmaceutical
Curated by ChEMBL
Affinity DataEC50: 3.90nMAssay Description:Agonist activity at human EP2 receptor expressed in CHO cells assessed as increase in intracellular cAMP level after 30 mins by HTRF methodMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Ono Pharmaceutical
Curated by ChEMBL
Ono Pharmaceutical
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at PK2-tagged human EP2 receptor expressed in HEK293 cells assessed as induction of EA-tagged beta-arrestin recruitment incubated fo...More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Ono Pharmaceutical
Curated by ChEMBL
Ono Pharmaceutical
Curated by ChEMBL
Affinity DataEC50: 260nMAssay Description:Agonist activity at human EP3 receptor expressed in CHO cells assessed as increase in intracellular calcium level by fluorescence based analysisMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Ono Pharmaceutical
Curated by ChEMBL
Ono Pharmaceutical
Curated by ChEMBL
Affinity DataEC50: 160nMAssay Description:Agonist activity at human EP1 receptor expressed in CHO cells assessed as increase in intracellular calcium level by fluorescence based analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 380nMAssay Description:Agonist activity at human FP receptor expressed in human Chem1 cells assessed as increase in intracellular calcium level by fluorescence based analys...More data for this Ligand-Target Pair