BDBM50170182 3,4-Dichloro-N-[4-(4-dimethylamino-quinazolin-2-ylamino)-cyclohexyl]-benzamide::CHEMBL362400

SMILES CN(C)c1nc(N[C@@H]2CC[C@@H](CC2)NC(=O)c2ccc(Cl)c(Cl)c2)nc2ccccc12

InChI Key InChIKey=UGUPGQUFTPDBTH-IYBDPMFKSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50170182   

TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50170182(3,4-Dichloro-N-[4-(4-dimethylamino-quinazolin-2-yl...)
Affinity DataIC50:  5nMAssay Description:Inhibitory activity against human CA-MCH-R1 (Melanin-concentrating hormone receptor 1) by using [125I](Phe13,Tyr19)MCH as radioligand expressed in HE...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50170182(3,4-Dichloro-N-[4-(4-dimethylamino-quinazolin-2-yl...)
Affinity DataIC50:  47nMAssay Description:Inhibitory activity against alpha-2A adrenergic receptor by using [3H]MK-912 as radioligand expressed in COS-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed