BDBM50170831 CHEMBL188343::N*6*-Cyclohexyl-N*2*-(4-morpholin-4-yl-phenyl)-9H-purine-2,6-diamine::N6-cyclohexyl-N2-(4-morpholinophenyl)-9H-purine-2,6-diamine::N~6~-cyclohexyl-N~2~-(4-morpholin-4-ylphenyl)-9H-purine-2,6-diamine
SMILES C1CCC(CC1)Nc1nc(Nc2ccc(cc2)N2CCOCC2)nc2nc[nH]c12
InChI Key InChIKey=ZFLJHSQHILSNCM-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50170831
TargetAdenosine receptor A3(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 660nMAssay Description:Inhibition of [125I]- AB-MECA binding to human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetAdenosine receptor A1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Percent inhibition of [3H]-DPCPX binding to human adenosine A1 receptor expressed in CHO cells at 10 uMMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Percent inhibition of [3H]ZM241,385 binding to human adenosine A2a receptor expressed in CHO cells at 10 uMMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of recombinant full-length His-tagged human Aurora A expressed in baculovirus expression systemMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant full-length His-tagged human Aurora B expressed in baculovirus expression systemMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of recombinant full-length His-tagged human Aurora C expressed in baculovirus expression systemMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human TTK-mediated MAD1/MAD2 complex phosphorylation after 1 hr by scintillation counting analysis in presence of gamma-[32P]ATPMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Mus musculus)
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of MEK1 in mouse C2C12 by ERK2 phosphorylation assayMore data for this Ligand-Target Pair